Intrinsic role of coagulase negative staphylococci norA -like efflux system in fluoroquinolones resistance

NorA is a multidrug transporter that exports structurally distinct compounds including fluoroquinolones. In this study like genes of ( ) and ( ) were identified and sequenced. The nucleotide identity of and with was 75.3 and 74.1%, respectively, and the amino acid identity 87.7 and 86%, respectively. Inactivation of increased the ciprofloxacin susceptibility of DH5α carrying the pB SK 198 EZ cat plasmid.