The PSIPRED Protein Analysis Workbench: 20 years on

The PSIPRED Workbench is a web server offering a range of predictive methods to the bioscience community for 20 years. Here, we present the work we have completed to update the PSIPRED Protein Analysis Workbench and make it ready for the next 20 years. The main focus of our recent website upgrade wo...

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Veröffentlicht in:	Nucleic acids research 2019-07, Vol.47 (W1), p.W402-W407
Hauptverfasser:	Buchan, Daniel W A, Jones, David T
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Binding Sites Gene Ontology - history Gene Ontology - trends History, 21st Century Internet Models, Molecular Molecular Sequence Annotation - history Molecular Sequence Annotation - methods Protein Binding Protein Conformation, alpha-Helical Protein Conformation, beta-Strand Protein Interaction Domains and Motifs Proteins - chemistry Proteins - history Sequence Alignment Sequence Homology, Amino Acid Software - history Web Server Issue
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Beschreibung
Zusammenfassung:	The PSIPRED Workbench is a web server offering a range of predictive methods to the bioscience community for 20 years. Here, we present the work we have completed to update the PSIPRED Protein Analysis Workbench and make it ready for the next 20 years. The main focus of our recent website upgrade work has been the acceleration of analyses in the face of increasing protein sequence database size. We additionally discuss any new software, the new hardware infrastructure, our webservices and web site. Lastly we survey updates to some of the key predictive algorithms available through our website.
ISSN:	0305-1048 1362-4962
DOI:	10.1093/nar/gkz297