A Reversible Gastric Uptake of Bone Scintigraphy in a Patient with Hypercalcemia

Hypercalcemia is a severe complication in cases of vitamin D intoxication that can result in metastatic calcification. We herein report a female case with hypercalcemia due to eldecalcitol administration associated with the increased uptake of technetium-99m hydroxymethylene diphosphonate (99mTc-HMD...

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Veröffentlicht in:Internal Medicine 2019/06/01, Vol.58(11), pp.1583-1586
Hauptverfasser: Fukasawa, Hirotaka, Ide, Saki, Kaneko, Mai, Ishibuchi, Kento, Niwa, Hiroki, Yasuda, Hideo, Furuya, Ryuichi
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Sprache:eng
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Zusammenfassung:Hypercalcemia is a severe complication in cases of vitamin D intoxication that can result in metastatic calcification. We herein report a female case with hypercalcemia due to eldecalcitol administration associated with the increased uptake of technetium-99m hydroxymethylene diphosphonate (99mTc-HMDP) as the bone-scanning agent in the stomach. A histologic assessment using biopsy specimens identified metastatic calcification of the stomach. After the normalization of serum calcium levels, the gastric uptake of 99mTc-HMDP disappeared. This case indicates the usefulness of bone scintigraphy with 99mTc-HMDP to detect visceral metastatic calcification and to monitor its therapeutic effects in patients with hypercalcemia.
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.2115-18