Depression, lifestyle factors and cognitive function in people living with HIV and comparable HIV‐negative controls

Objectives We investigated whether differences in cognitive performance between people living with HIV (PLWH) and comparable HIV‐negative people were mediated or moderated by depressive symptoms and lifestyle factors. Methods A cross‐sectional study of 637 ‘older’ PLWH aged ≥ 50 years, 340 ‘younger’...

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Veröffentlicht in:	HIV medicine 2019-04, Vol.20 (4), p.274-285
Hauptverfasser:	De Francesco, D, Underwood, J, Bagkeris, E, Boffito, M, Post, FA, Mallon, PWG, Vera, JH, Williams, I, Anderson, J, Johnson, M, Sabin, CA, Winston, A, Babalis, Daphne, Burgess, Laura, Mallon, Paddy, Sachikonye, Memory, Asboe, David, Garvey, Lucy, Pozniak, Anton, Clarke, Amanda, Bexley, Andrew, Richardson, Celia, Kirk, Sarah, Gleig, Rebecca, Bracchi, Margherita, Pagani, Nicole, Cerrone, Maddalena, Bradshaw, Daniel, Ferretti, Francesca, Higgs, Chris, Seah, Elisha, Fletcher, Stephen, Anthonipillai, Michelle, Moyes, Ashley, Deats, Katie, Syed, Irtiza, Matthews, Clive, Fernando, Peter, Chiwome, Chido, Hardwick, Shane, Mguni, Sifiso, Clark, Rebecca, Nevin‐Dolan, Rhiannon, Pelluri, Sambasivarao, Campbell, Lucy, Yurdakul, Selin, Okumu, Sara, Pollard, Louise, Santana‐Suarez, Beatriz, Macken, Alan, Ghavani‐Kia, Bijan, Maher, Joanne, Byrne, Maria, Flaherty, Ailbhe, Babu, Sumesh, Otiko, Damilola, Phillips, Laura, Laverick, Rosanna, Beynon, Michelle, Salz, Anna‐Lena, Severn, Abigail, Tembo, Lavender, Stott, Matthew, McDonald, Linda, Dransfield, Felix, Whitehouse, Andrew, Ngwu, Nnenna, Hemat, Nargis, Jones, Martin, Carroll, Anne, Kinloch, Sabine, Youle, Mike, Madge, Sara
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Cognition cognitive disorder cognitive function Cross-Sectional Studies depression Depressive Disorder - psychology Female HIV HIV Infections - psychology HIV‐associated neurocognitive disorders Humans Life Style Male Middle Aged Original Research people living with HIV Substance-Related Disorders - psychology Young Adult
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Beschreibung
Zusammenfassung:	Objectives We investigated whether differences in cognitive performance between people living with HIV (PLWH) and comparable HIV‐negative people were mediated or moderated by depressive symptoms and lifestyle factors. Methods A cross‐sectional study of 637 ‘older’ PLWH aged ≥ 50 years, 340 ‘younger’ PLWH aged
ISSN:	1464-2662 1468-1293
DOI:	10.1111/hiv.12714