Transcriptome Analysis of Long-lived Drosophila melanogaster E(z) Mutants Sheds Light on the Molecular Mechanisms of Longevity

The E ( z ) histone methyltransferase heterozygous mutation in Drosophila is known to increase lifespan and stress resistance. However, the longevity mechanisms of E ( z ) mutants have not been revealed. Using genome-wide transcriptome analysis, we demonstrated that lifespan extension, increase of r...

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