Survival benefit of accepting livers from deceased donors over 70 years old

Livers from older donors (OLDs; age ≥70) are risky and often declined; however, it is likely that some candidates will benefit from OLDs versus waiting for younger ones. To characterize the survival benefit of accepting OLD grafts, we used 2009‐2017 SRTR data to identify 24 431 adult liver transplan...

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Veröffentlicht in:American journal of transplantation 2019-07, Vol.19 (7), p.2020-2028
Hauptverfasser: Haugen, Christine E., Bowring, Mary G., Holscher, Courtenay M., Jackson, Kyle R., Garonzik‐Wang, Jacqueline, Cameron, Andrew M., Philosophe, Benjamin, McAdams‐DeMarco, Mara, Segev, Dorry L.
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Sprache:eng
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Zusammenfassung:Livers from older donors (OLDs; age ≥70) are risky and often declined; however, it is likely that some candidates will benefit from OLDs versus waiting for younger ones. To characterize the survival benefit of accepting OLD grafts, we used 2009‐2017 SRTR data to identify 24 431 adult liver transplant (LT) candidates who were offered OLD grafts eventually accepted by someone. Outcomes from the time‐of‐offer were compared between candidates who accepted an OLD graft and matched controls within MELD ± 2 who declined the same offer. Candidates who accepted OLD grafts (n = 1311) were older (60.5 vs. 57.8 years, P 
ISSN:1600-6135
1600-6143
DOI:10.1111/ajt.15250