Prognostic evaluation of resectable colorectal cancer using platelet-associated indicators

Colorectal cancer (CRC) represents the third most common malignancy worldwide. The aim of the present study was to investigate the predictive values of platelet-associated indicators, including platelet count (PLT), plateletcrit (PCT), mean platelet volume (MPV) and platelet distribution width (PDW)...

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Veröffentlicht in:Oncology letters 2019-07, Vol.18 (1), p.571-580
Hauptverfasser: Qian, Weihua, Ge, Xin-Xin, Wu, Jing, Gong, Fei-Ran, Wu, Meng-Yao, Xu, Meng-Dan, Lian, Lian, Wang, Wen-Jie, Li, Wei, Tao, Min
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Sprache:eng
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Zusammenfassung:Colorectal cancer (CRC) represents the third most common malignancy worldwide. The aim of the present study was to investigate the predictive values of platelet-associated indicators, including platelet count (PLT), plateletcrit (PCT), mean platelet volume (MPV) and platelet distribution width (PDW) in patients with resectable CRC. The current retrospective study included 153 patients who were pathologically diagnosed with resectable CRC. The patients were divided into two groups according to the median value of PLT, PCT, MPV or PDW. To evaluate the changes in PLT, PCT, MPV and PDW following resection and adjuvant chemotherapy, the concept of post-/pre-treatment PLT, PCT, MPV and PDW ratios was introduced, where
ISSN:1792-1074
1792-1082
DOI:10.3892/ol.2019.10388