Neural effects of inflammation, cardiovascular disease, and HIV: Parallel, perpendicular, or progressive?

Highlights • Chronic inflammation plays an instrumental role in cardiovascular disease. • People living with HIV frequently have co-morbid inflammatory disorders. • Cardiovascular disease, inflammation, and HIV interact to precipitate neural damage.

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Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience 2015-08, Vol.302, p.165-173
Hauptverfasser:	Nemeth, C.L, Bekhbat, M, Neigh, G.N
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS Animals cardiovascular Cardiovascular Diseases - epidemiology Cardiovascular Diseases - pathology cerebrovascular Cytokines - metabolism Disease Progression HIV HIV Infections - epidemiology HIV Infections - pathology Human immunodeficiency virus Humans immune inflammation Inflammation - epidemiology Inflammation - pathology Macrophages - metabolism Macrophages - pathology Microglia - metabolism Microglia - pathology Neurology Risk Factors
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Beschreibung
Zusammenfassung:	Highlights • Chronic inflammation plays an instrumental role in cardiovascular disease. • People living with HIV frequently have co-morbid inflammatory disorders. • Cardiovascular disease, inflammation, and HIV interact to precipitate neural damage.
ISSN:	0306-4522 1873-7544
DOI:	10.1016/j.neuroscience.2014.09.016