Decolonization to Reduce Postdischarge Infection Risk among MRSA Carriers

Decolonization to Reduce Postdischarge Infection Risk among MRSA Carriers

Colonization with methicillin-resistant Staphylococcus aureus is associated with increased infection risk after hospital discharge. In a multicenter, randomized trial, a program of MRSA decolonization at home led to a significantly lower risk of MRSA infection over a 1-year period than hygiene educa...

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Veröffentlicht in:The New England journal of medicine 2019-02, Vol.380 (7), p.638-650
Hauptverfasser: Huang, Susan S, Singh, Raveena, McKinnell, James A, Park, Steven, Gombosev, Adrijana, Eells, Samantha J, Gillen, Daniel L, Kim, Diane, Rashid, Syma, Macias-Gil, Raul, Bolaris, Michael A, Tjoa, Thomas, Cao, Chenghua, Hong, Suzie S, Lequieu, Jennifer, Cui, Eric, Chang, Justin, He, Jiayi, Evans, Kaye, Peterson, Ellena, Simpson, Gail, Robinson, Philip, Choi, Chester, Bailey, Charles C, Leo, James D, Amin, Alpesh, Goldmann, Donald, Jernigan, John A, Platt, Richard, Septimus, Edward, Weinstein, Robert A, Hayden, Mary K, Miller, Loren G
Format: Artikel
Sprache:eng
Schlagworte:
Administration, Intranasal
Adult
Aged
Anti-Bacterial Agents - therapeutic use
Anti-Infective Agents, Local - therapeutic use
Antibiotics
Baths
Carrier State
Chlorhexidine
Chlorhexidine - therapeutic use
Comorbidity
Disease control
Disease Transmission, Infectious - prevention & control
Disinfection
Drug resistance
Education
Female
Follow-Up Studies
Hospitalization
Hospitalization - statistics & numerical data
Hospitals
Humans
Hygiene
Hygiene - education
Infection Control - methods
Infectious diseases
Male
Medical records
Methicillin
Methicillin-Resistant Staphylococcus aureus - isolation & purification
Middle Aged
Mouthwashes
Mupirocin
Mupirocin - therapeutic use
Nursing homes
Patient Education as Topic
Patients
Skin
Staphylococcal Infections - drug therapy
Staphylococcal Infections - prevention & control
Staphylococcal Infections - transmission
Staphylococcus aureus
Staphylococcus infections
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Beschreibung
Zusammenfassung:Colonization with methicillin-resistant Staphylococcus aureus is associated with increased infection risk after hospital discharge. In a multicenter, randomized trial, a program of MRSA decolonization at home led to a significantly lower risk of MRSA infection over a 1-year period than hygiene education alone.
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMoa1716771