Lower DHEA-S levels predict disease and worse outcomes in post-menopausal women with idiopathic, connective tissue disease- and congenital heart disease-associated pulmonary arterial hypertension

High oestradiol (E2) and low dehydroepiandrosterone-sulfate (DHEA-S) levels are risk factors for pulmonary arterial hypertension (PAH) in men, but whether sex hormones are related to PAH in women is unknown.Post-menopausal women aged ≥55 years with PAH were matched by age and body mass index to wome...

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Veröffentlicht in:	The European respiratory journal 2018-06, Vol.51 (6), p.1800467-1800467
Hauptverfasser:	Baird, Grayson L, Archer-Chicko, Christine, Barr, R Graham, Bluemke, David A, Foderaro, Andrew E, Fritz, Jason S, Hill, Nicholas S, Kawut, Steven M, Klinger, James R, Lima, Joao A C, Mullin, Christopher J, Ouyang, Pamela, Palevsky, Harold I, Palmisicano, Amy J, Pinder, Diane, Preston, Ioana R, Roberts, Kari E, Smith, K Akaya, Walsh, Thomas, Whittenhall, Mary, Ventetuolo, Corey E
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Body Mass Index Cardiovascular diseases Case-Control Studies Connective Tissue Diseases - complications Coronary artery disease Dehydroepiandrosterone Dehydroepiandrosterone Sulfate - blood Estradiol - blood Female Health risk assessment Heart Defects, Congenital - complications Heart diseases Hemodynamics Hormone replacement therapy Humans Hypertension Hypertension, Pulmonary - blood Hypertension, Pulmonary - complications Lung diseases Male Middle Aged Postmenopause - blood Proportional Hazards Models Pulmonary hypertension Risk Factors Sex hormones Sulfate Ventricle Walk Test
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