A Cohort Study of the Impact of Carbapenem-Resistant Enterobacteriaceae Infections on Mortality of Patients Presenting with Sepsis

The objective of this study is to evaluate the impact of carbapenem-resistant (CRE) infection on sepsis 30-day mortality. A retrospective cohort of patients >18 years old with sepsis and organ dysfunction or septic shock was conducted. Univariate analysis was done for variables potentially relate...

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Veröffentlicht in:	mSphere 2019-04, Vol.4 (2)
Hauptverfasser:	Sabino, Sabrina, Soares, Silvia, Ramos, Fabiano, Moretti, Miriane, Zavascki, Alexandre P, Rigatto, Maria Helena
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Anti-Bacterial Agents - pharmacology Antibiotics Antimicrobial agents Bacteria Bacterial infections Blood tests Carbapenem-Resistant Enterobacteriaceae - drug effects Chronic obstructive pulmonary disease Cirrhosis Clinical Science and Epidemiology Cohort analysis Comorbidity CRE bacteria Drug Resistance, Multiple, Bacterial Enterobacteriaceae Enterobacteriaceae Infections - blood Enterobacteriaceae Infections - mortality Epidemiology Female Gram-negative bacteria HIV Hospitals Human immunodeficiency virus Humans Identification Infectious diseases Liver cirrhosis Male Middle Aged Mortality Multidrug resistance Organ Dysfunction Scores Patients Prevalence Retrospective Studies Sepsis Sepsis - microbiology Sepsis - mortality Septic shock Shock, Septic Staphylococcus infections Statistical analysis Variables Ventilators
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Zusammenfassung:	The objective of this study is to evaluate the impact of carbapenem-resistant (CRE) infection on sepsis 30-day mortality. A retrospective cohort of patients >18 years old with sepsis and organ dysfunction or septic shock was conducted. Univariate analysis was done for variables potentially related to 30-day mortality, and the ones with values of
ISSN:	2379-5042 2379-5042
DOI:	10.1128/mSphere.00052-19