Serine-threonine kinases in TCR signaling

TCR engagement triggers activation of downstream kinases. Navarro and Cantrell discuss how the network of serine/threonine kinases instruct T cell metabolism to participate in immune responses. T lymphocyte proliferation and differentiation are controlled by signaling pathways initiated by the T cel...

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Veröffentlicht in:	Nature immunology 2014-09, Vol.15 (9), p.808-814
Hauptverfasser:	Navarro, María N, Cantrell, Doreen A
Format:	Artikel
Sprache:	eng
Schlagworte:	631/250/1619/554/1775 631/250/516 Antigen receptors, T cell Biomedicine Cell Differentiation - immunology Cell Proliferation - physiology Cellular signal transduction Humans Immune response Immunology Infectious Diseases Lymphocyte Activation - immunology Lymphocytes Physiological aspects Protein kinases Protein-Serine-Threonine Kinases - immunology Receptors Receptors, Antigen, T-Cell - immunology review-article Serine Signal Transduction - immunology T cells T-Lymphocytes - immunology Threonine
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