High-Dose Vitamin D Supplementation During Pregnancy and Asthma in Offspring at the Age of 6 Years

This long-term follow-up of a randomized trial reporting no apparent effect of high-dose vs standard-dose prenatal vitamin D supplementation on wheezing in children at the age of 3 years extends the findings an additional 3 years and describes asthma risk at the age of 6 years.

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Bibliographische Detailangaben
Veröffentlicht in:	JAMA : the journal of the American Medical Association 2019-03, Vol.321 (10), p.1003-1005
Hauptverfasser:	Brustad, Nicklas, Eliasen, Anders U, Stokholm, Jakob, Bønnelykke, Klaus, Bisgaard, Hans, Chawes, Bo L
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Asthma Asthma - diagnosis Asthma - epidemiology Asthma - prevention & control Child Child, Preschool Children Dietary Supplements Dose-Response Relationship, Drug Female Follow-Up Studies Humans Letter Letters Male Offspring Pregnancy Prenatal experience Prevalence Regression Analysis Research Letter Respiratory Function Tests Respiratory Sounds Supplements Vitamin D Vitamin D - administration & dosage Vitamins - administration & dosage Wheezing
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Beschreibung
Zusammenfassung:	This long-term follow-up of a randomized trial reporting no apparent effect of high-dose vs standard-dose prenatal vitamin D supplementation on wheezing in children at the age of 3 years extends the findings an additional 3 years and describes asthma risk at the age of 6 years.
ISSN:	0098-7484 1538-3598
DOI:	10.1001/jama.2019.0052