Pharmacokinetics, Safety, and Dosing of Novel Pediatric Levofloxacin Dispersible Tablets in Children with Multidrug-Resistant Tuberculosis Exposure

This study characterized the pharmacokinetics of novel 100-mg levofloxacin dispersible tablets in 24 children aged

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Bibliographische Detailangaben
Veröffentlicht in:	Antimicrobial agents and chemotherapy 2019-04, Vol.63 (4)
Hauptverfasser:	Garcia-Prats, Anthony J, Purchase, Susan E, Osman, Muhammad, Draper, Heather R, Schaaf, H Simon, Wiesner, Lubbe, Denti, Paolo, Hesseling, Anneke C
Format:	Artikel
Sprache:	eng
Schlagworte:	Antitubercular Agents Antitubercular Agents - administration & dosage Antitubercular Agents - adverse effects Antitubercular Agents - pharmacokinetics Biological Availability Child, Preschool Female Humans Infant Levofloxacin Levofloxacin - administration & dosage Levofloxacin - adverse effects Levofloxacin - pharmacokinetics Male Pharmacology Placebos Tablets Tuberculosis, Multidrug-Resistant Tuberculosis, Multidrug-Resistant - drug therapy Tuberculosis, Multidrug-Resistant - prevention & control
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Beschreibung
Zusammenfassung:	This study characterized the pharmacokinetics of novel 100-mg levofloxacin dispersible tablets in 24 children aged
ISSN:	0066-4804 1098-6596
DOI:	10.1128/AAC.01865-18