The impact of direct‐acting antiviral agents on liver and kidney transplant costs and outcomes

Direct‐acting antiviral medications (DAAs) have revolutionized care for hepatitis C positive (HCV+) liver (LT) and kidney (KT) transplant recipients. Scientific Registry of Transplant Recipients registry data were integrated with national pharmaceutical claims (2007‐2016) to identify HCV treatments...

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Veröffentlicht in:American journal of transplantation 2018-10, Vol.18 (10), p.2473-2482
Hauptverfasser: Axelrod, D. A., Schnitzler, M. A., Alhamad, T., Gordon, F., Bloom, R. D., Hess, G. P., Xiao, H., Nazzal, M., Segev, D. L., Dharnidharka, V. R., Naik, A. S., Lam, N. N., Ouseph, R., Kasiske, B. L., Durand, C. M., Lentine, K. L.
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Sprache:eng
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Zusammenfassung:Direct‐acting antiviral medications (DAAs) have revolutionized care for hepatitis C positive (HCV+) liver (LT) and kidney (KT) transplant recipients. Scientific Registry of Transplant Recipients registry data were integrated with national pharmaceutical claims (2007‐2016) to identify HCV treatments before January 2014 (pre‐DAA) and after (post‐DAA), stratified by donor (D) and recipient (R) serostatus and payer. Pre‐DAA, 18% of HCV+ LT recipients were treated within 3 years and without differences by donor serostatus or payer. Post‐DAA, only 6% of D‐/R+ recipients, 19.8% of D+/R+ recipients with public insurance, and 11.3% with private insurance were treated within 3 years (P 
ISSN:1600-6135
1600-6143
1600-6143
DOI:10.1111/ajt.14895