Simultaneous Presentation of Waldenström's Macroglobulinemia and MYD88 Gene Mutation with Multiple Myeloma

Simultaneous Presentation of Waldenström's Macroglobulinemia and MYD88 Gene Mutation with Multiple Myeloma

Waldenström's macroglobulinemia (WM) and multiple myeloma (MM) are two distinct forms of mature hematologic B-cell malignancies. A missense somatic mutation in MYD88 gene (MYD88L265P) has been found in hematologic B-cell malignancies. The simultaneous presentation of Waldenström's macroglo...

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Veröffentlicht in:Curēus (Palo Alto, CA) CA), 2019-01, Vol.11 (1), p.e3822
Hauptverfasser: Awada, Hassan, Kewan, Tariq, Covut, Fahrettin, Daw, Hamed, Haddad, Abdo
Format: Artikel
Sprache:eng
Schlagworte:
Biopsy
Bone marrow
Case reports
Genetics
Internal Medicine
Lymphoma
Medical imaging
Multiple myeloma
Mutation
NMR
Nuclear magnetic resonance
Oncology
Pain
Proteins
Vertebrae
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Zusammenfassung:Waldenström's macroglobulinemia (WM) and multiple myeloma (MM) are two distinct forms of mature hematologic B-cell malignancies. A missense somatic mutation in MYD88 gene (MYD88L265P) has been found in hematologic B-cell malignancies. The simultaneous presentation of Waldenström's macroglobulinemia and MYD88 mutation with multiple myeloma in the same patient is very rare and only a few cases have been reported in the literature.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.3822