Genome‐wide profiling of mRNA and lncRNA expression in dengue fever and dengue hemorrhagic fever

Genome‐wide profiling of mRNA and lncRNA expression in dengue fever and dengue hemorrhagic fever

Dengue fever (DF) and dengue hemorrhagic fever (DHF) are recurrent diseases that are widespread in the tropics. Here, we identified candidate genes associated with these diseases by performing integrated analyses of DF (GSE51808) and DHF (GSE18090) microarray datasets in the Gene Expression Omnibus...

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Veröffentlicht in:FEBS open bio 2019-03, Vol.9 (3), p.468-477
Hauptverfasser: Zhong, Xiao‐Lan, Liao, Xiao‐Ming, Shen, Fei, Yu, Hai‐Jian, Yan, Wen‐Sheng, Zhang, Yun‐Fang, Ye, Jia‐Jun, Lv, Zhi‐Ping
Format: Artikel
Sprache:eng
Schlagworte:
Biomarkers - analysis
DEGs
DElncRNAs
Dengue - genetics
dengue fever
dengue hemorrhagic fever
Gene Expression Profiling
genome profiling
Humans
integrated analysis
RNA, Long Noncoding - genetics
RNA, Messenger - genetics
Severe Dengue - genetics
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Zusammenfassung:Dengue fever (DF) and dengue hemorrhagic fever (DHF) are recurrent diseases that are widespread in the tropics. Here, we identified candidate genes associated with these diseases by performing integrated analyses of DF (GSE51808) and DHF (GSE18090) microarray datasets in the Gene Expression Omnibus (GEO). In all, we identified 7635 differentially expressed genes (DEGs) in DF and 8147 DEGs in DHF as compared to healthy controls (P 
ISSN:2211-5463
2211-5463
DOI:10.1002/2211-5463.12576