Single-cell RNA-seq of cultured human adipose-derived mesenchymal stem cells

Adipose-derived mesenchymal stem cells (ADSCs) show considerable promise for clinical applications in regenerative medicine. We performed a large-scale single-cell transcriptomic sequencing of 24,358 cultured human ADSCs from three donors. We provide a high-quality dataset, which would be a valuable...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Scientific data 2019-02, Vol.6 (1), p.190031-190031, Article 190031
Hauptverfasser: Liu, Xuanyu, Xiang, Qinqin, Xu, Fen, Huang, Jiuzuo, Yu, Nanze, Zhang, Qixu, Long, Xiao, Zhou, Zhou
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Adipose-derived mesenchymal stem cells (ADSCs) show considerable promise for clinical applications in regenerative medicine. We performed a large-scale single-cell transcriptomic sequencing of 24,358 cultured human ADSCs from three donors. We provide a high-quality dataset, which would be a valuable resource for dissecting the intrapopulation heterogeneity of cultured ADSCs as well as interrogating lineage priming patterns for any interested lineages at single-cell resolution. Design Type(s) transcription profiling design • sequence analysis objective Measurement Type(s) adipose tissue derived mesenchymal stem cell Technology Type(s) single cell nucleic acid sequencing protocol Factor Type(s) Sample Characteristic(s) Homo sapiens • adipose tissue Machine-accessible metadata file describing the reported data (ISA-Tab format)
ISSN:2052-4463
2052-4463
DOI:10.1038/sdata.2019.31