Graphene Oxide as a Multifunctional Platform for Intracellular Delivery, Imaging, and Cancer Sensing

Graphene oxide (GO), the most common derivative of graphene, is an exceptional nanomaterial that possesses multiple physical properties critical for biomedical applications. GO exhibits pH-dependent fluorescence emission in the visible/near-infrared, providing a possibility of molecular imaging and...

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Veröffentlicht in:Scientific reports 2019-01, Vol.9 (1), p.416, Article 416
Hauptverfasser: Campbell, E., Hasan, Md. Tanvir, Pho, Christine, Callaghan, K., Akkaraju, G. R., Naumov, A. V.
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Sprache:eng
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Zusammenfassung:Graphene oxide (GO), the most common derivative of graphene, is an exceptional nanomaterial that possesses multiple physical properties critical for biomedical applications. GO exhibits pH-dependent fluorescence emission in the visible/near-infrared, providing a possibility of molecular imaging and pH-sensing. It is also water soluble and has a substantial platform for functionalization, allowing for the delivery of multiple therapeutics. GO physical properties are modified to enhance cellular internalization, producing fluorescent nanoflakes with low (
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-018-36617-4