Regulation of iNOS on Immune Cells and Its Role in Diseases

Regulation of iNOS on Immune Cells and Its Role in Diseases

In recent years, there have been many studies on the function of nitric oxide synthase (NOS) in experimental animals and humans. This review analyzes and explores the relationship between inducible nitric oxide synthase (iNOS) and T cells, macrophages, and dendritic cell et al. differentiation using...

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Veröffentlicht in:International journal of molecular sciences 2018-11, Vol.19 (12), p.3805
Hauptverfasser: Xue, Qingjie, Yan, Yingchun, Zhang, Ruihua, Xiong, Huabao
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Binding sites
Cell differentiation
Dendritic cells
Dendritic Cells - enzymology
Disease
Humans
Immune system
Inflammatory bowel disease
Inflammatory diseases
Ligands
Lymphocytes
Lymphocytes T
Macrophages
Macrophages - enzymology
Nitric oxide
Nitric Oxide Synthase Type II - genetics
Nitric Oxide Synthase Type II - metabolism
Nitric-oxide synthase
Pathogenesis
Pathogens
Protein expression
Proteins
Review
T-Lymphocytes - enzymology
Transcription factors
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Zusammenfassung:In recent years, there have been many studies on the function of nitric oxide synthase (NOS) in experimental animals and humans. This review analyzes and explores the relationship between inducible nitric oxide synthase (iNOS) and T cells, macrophages, and dendritic cell et al. differentiation using data based on laboratory research, highlighting recent NOS laboratory research. Our insights into research prospects and directions are also presented.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms19123805