Inhibiting antibiotic-resistant Enterobacteriaceae by microbiota-mediated intracellular acidification

, , and other members of the Enterobacteriaceae family are common human pathogens that have acquired broad antibiotic resistance, rendering infection by some strains virtually untreatable. Enterobacteriaceae are intestinal residents, but generally represent

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Bibliographische Detailangaben
Veröffentlicht in:	The Journal of experimental medicine 2019-01, Vol.216 (1), p.84-98
Hauptverfasser:	Sorbara, Matthew T, Dubin, Krista, Littmann, Eric R, Moody, Thomas U, Fontana, Emily, Seok, Ruth, Leiner, Ingrid M, Taur, Ying, Peled, Jonathan U, van den Brink, Marcel R M, Litvak, Yael, Bäumler, Andreas J, Chaubard, Jean-Luc, Pickard, Amanda J, Cross, Justin R, Pamer, Eric G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Colon - metabolism Colon - microbiology Colon - pathology Drug Resistance, Bacterial Enterobacteriaceae - growth & development Enterobacteriaceae Infections - metabolism Enterobacteriaceae Infections - microbiology Enterobacteriaceae Infections - pathology Fatty Acids - metabolism Female Gastrointestinal Microbiome Humans Hydrogen-Ion Concentration Male Mice
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	, , and other members of the Enterobacteriaceae family are common human pathogens that have acquired broad antibiotic resistance, rendering infection by some strains virtually untreatable. Enterobacteriaceae are intestinal residents, but generally represent
ISSN:	0022-1007 1540-9538
DOI:	10.1084/jem.20181639