Clinicopathological and prognostic significance of GLUT1 in breast cancer: A meta-analysis

Previous studies examining the prognostic value of glucose transporter 1 in breast cancer have yielded inconsistent results. We, therefore, performed a meta-analysis to clarify this issue. The research was reported according to the preferred reporting items for systematic reviews and meta-analyses (...

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Veröffentlicht in:	Medicine (Baltimore) 2018-11, Vol.97 (48), p.e12961-e12961
Hauptverfasser:	Deng, Yu, Zou, Jialing, Deng, Ting, Liu, Junying
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor Breast Neoplasms - genetics Breast Neoplasms - pathology Disease-Free Survival Female Glucose Transporter Type 1 - biosynthesis Humans Lymphatic Metastasis - genetics Lymphatic Metastasis - pathology Neoplasm Grading Prognosis Receptor, ErbB-2 - biosynthesis Survival Analysis Systematic Review and Meta-Analysis Tumor Burden
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Zusammenfassung:	Previous studies examining the prognostic value of glucose transporter 1 in breast cancer have yielded inconsistent results. We, therefore, performed a meta-analysis to clarify this issue. The research was reported according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. Relevant studies were retrieved from PubMed, Web of Science, EMBASE, and Cochrane library. A total of 7 reports with 1861 patients were finally chosen. GLUT1 overexpression was found to be associated with high histological grade (OR = 3.74, 95% CI = 2.45-5.69, P
ISSN:	0025-7974 1536-5964
DOI:	10.1097/MD.0000000000012961