Long non-coding RNA LOC285194 functions as a tumor suppressor by targeting p53 in non-small cell lung cancer

Recently, LOC285194 has shown a potential tumor-suppressor function in several types of human cancers, but its function in non-small cell lung cancer (NSCLC) remains unknown. This study intended to investigate the biological role of LOC285194 and its clinical significance in NSCLC. LOC285194 was det...

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Veröffentlicht in:	Oncology reports 2019-01, Vol.41 (1), p.15-26
Hauptverfasser:	Zhou, Huaping, Chen, Allen, Shen, Jianfei, Zhang, Xiaoxue, Hou, Min, Li, Jin, Chen, Jingyi, Zou, Huan, Zhang, Yingfei, Deng, Qianren, She, Kelin, Shi, Xiaoshun, He, Jianxing
Format:	Artikel
Sprache:	eng
Schlagworte:	Biotechnology Cancer therapies Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - mortality Carcinoma, Non-Small-Cell Lung - pathology Care and treatment Cell growth Cell Line, Tumor Cell Movement - genetics Cell Proliferation - genetics Development and progression Disease-Free Survival Experiments Female Gene expression Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Gene therapy Genes, Tumor Suppressor Genetic aspects Health aspects Histology Humans Innovations Kaplan-Meier Estimate Lung - pathology Lung cancer Lung Neoplasms - genetics Lung Neoplasms - mortality Lung Neoplasms - pathology Lymphatic system Male Medical prognosis Medical research Metastasis Middle Aged Mutation Non-small cell lung cancer Plasmids Prognosis RNA RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism Survival Rate Tumor suppressor genes Tumor Suppressor Protein p53 - genetics Tumor Suppressor Protein p53 - metabolism
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