Continuous monitoring after atrial fibrillation ablation: the LINQ AF study
To study device performance, arrhythmia recurrence characteristics, and methods of outcome assessment using a novel implantable cardiac monitor (ICM) in patients undergoing ablation for atrial fibrillation (AF). In 419 consecutive patients undergoing first-time catheter ablation for symptomatic paro...
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Veröffentlicht in: | Europace (London, England) England), 2018-11, Vol.20 (FI_3), p.f312-f320 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | To study device performance, arrhythmia recurrence characteristics, and methods of outcome assessment using a novel implantable cardiac monitor (ICM) in patients undergoing ablation for atrial fibrillation (AF).
In 419 consecutive patients undergoing first-time catheter ablation for symptomatic paroxysmal (n = 224) or persistent (n = 195) AF an ICM was injected at the end of the procedure. Telemedicine staff ensured full episode transmission coverage and manually evaluated all automatic arrhythmia episodes. Device detection metrics were calculated for ≥2, ≥6, and ≥10 min AF detection durations. Four methods of outcome assessment were studied: continuous recurrence analysis, discontinuous recurrence analysis, AF-burden analysis, and analysis of individual rhythm profiles. A total of 43 673 automatic AF episodes were transmitted over a follow-up of 15 ± 6 months. Episode-based positive predictive values changed significantly with longer AF detection durations (70.5% for ≥2 min, 81.8% for ≥6 min, and 85.9% for ≥10 min). Patients with exclusive short episode recurrences (≥2 to 6 min and AF burden >0.1% as a standardized outcome definition for AF studies to come in the future. |
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ISSN: | 1099-5129 1532-2092 |
DOI: | 10.1093/europace/euy038 |