Developing a Minimally Structured Mathematical Model of Cancer Treatment with Oncolytic Viruses and Dendritic Cell Injections

Mathematical models of biological systems must strike a balance between being sufficiently complex to capture important biological features, while being simple enough that they remain tractable through analysis or simulation. In this work, we rigorously explore how to balance these competing interes...

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Veröffentlicht in:	Computational and mathematical methods in medicine 2018-01, Vol.2018 (2018), p.1-14
Hauptverfasser:	Gevertz, Jana L., Wares, Joanna R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Computer Simulation Dendritic Cells - immunology Dendritic Cells - transplantation Humans Mathematical Concepts Melanoma, Experimental - immunology Melanoma, Experimental - therapy Mice Models, Biological Neoplasms - immunology Neoplasms - therapy Oncolytic Virotherapy - statistics & numerical data Systems Biology
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