Evoked directional network characteristics of epileptogenic tissue derived from single pulse electrical stimulation

We investigated effective networks constructed from single pulse electrical stimulation (SPES) in epilepsy patients who underwent intracranial electrocorticography. Using graph analysis, we compared network characteristics of tissue within and outside the epileptogenic area. In 21 patients with subd...

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Veröffentlicht in:	Human brain mapping 2018-11, Vol.39 (11), p.4611-4622
Hauptverfasser:	van Blooijs, Dorien, Leijten, Frans S. S., van Rijen, Peter C., Meijer, Hil G. E., Huiskamp, Geertjan J. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult bidirectional network Brain Brain - physiopathology Brain - surgery Brain Mapping - methods Child Child, Preschool Convulsions & seizures Electric Stimulation - methods Electrical stimuli electrocorticography Electrocorticography - methods Electrodes Epilepsy Epilepsy - physiopathology Epilepsy - surgery epileptogenic zone Female Humans Male Middle Aged Models, Theoretical Neural Pathways - physiopathology Neural Pathways - surgery Patients Seizing Seizures single pulse electrical stimulation Stimulation surgery Young Adult
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Zusammenfassung:	We investigated effective networks constructed from single pulse electrical stimulation (SPES) in epilepsy patients who underwent intracranial electrocorticography. Using graph analysis, we compared network characteristics of tissue within and outside the epileptogenic area. In 21 patients with subdural electrode grids (1 cm interelectrode distance), we constructed a binary, directional network derived from SPES early responses (
ISSN:	1065-9471 1097-0193
DOI:	10.1002/hbm.24309