Fatal Measles Virus Infection After Rituximab-Containing Chemotherapy in a Previously Vaccinated Patient

Fatal Measles Virus Infection After Rituximab-Containing Chemotherapy in a Previously Vaccinated Patient

We report the case of a young patient treated with rituximab-containing chemotherapy who was infected with measles despite previous vaccination. Treatment with vitamin A, ribavirin, and immunoglobulins was started; nevertheless he developed severe pneumonitis and deceased. Broad vaccination coverage...

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Veröffentlicht in:Open forum infectious diseases 2018-11, Vol.5 (11), p.ofy244-ofy244
Hauptverfasser: Jent, Philipp, Trippel, Mafalda, Frey, Manuel, Pöllinger, Alexander, Berezowska, Sabina, Langer, Rupert, Furrer, Hansjakob, Béguelin, Charles
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Sprache:eng
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Zusammenfassung:We report the case of a young patient treated with rituximab-containing chemotherapy who was infected with measles despite previous vaccination. Treatment with vitamin A, ribavirin, and immunoglobulins was started; nevertheless he developed severe pneumonitis and deceased. Broad vaccination coverage is crucial in protecting vulnerable subjects.
ISSN:2328-8957
2328-8957
DOI:10.1093/ofid/ofy244