DARK Classics in Chemical Neuroscience: Cocaine

In this Review, we consider the story of cocaine from its humble origins in South America to its status as one of the most abused substances in 21st century society. The synthesis and biosynthesis of cocaine are discussed, as well as its pharmacokinetics, metabolism, pharmacology, and importance in...

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Veröffentlicht in:ACS chemical neuroscience 2018-10, Vol.9 (10), p.2358-2372
Hauptverfasser: Drake, Lindsey R, Scott, Peter J. H
Format: Artikel
Sprache:eng
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Zusammenfassung:In this Review, we consider the story of cocaine from its humble origins in South America to its status as one of the most abused substances in 21st century society. The synthesis and biosynthesis of cocaine are discussed, as well as its pharmacokinetics, metabolism, pharmacology, and importance in modern neuroscience and molecular imaging.
ISSN:1948-7193
1948-7193
DOI:10.1021/acschemneuro.8b00117