Procalcitonin-Guided Use of Antibiotics for Lower Respiratory Tract Infection

Differentiating acute bacterial infection from other causes of lower respiratory tract illness is challenging. In this trial, procalcitonin was investigated as a point-of-care test to aid in determining whether antibiotics were needed in the treatment of these illnesses.

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Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2018-07, Vol.379 (3), p.236-249
Hauptverfasser:	Huang, David T, Yealy, Donald M, Filbin, Michael R, Brown, Aaron M, Chang, Chung-Chou H, Doi, Yohei, Donnino, Michael W, Fine, Jonathan, Fine, Michael J, Fischer, Michelle A, Holst, John M, Hou, Peter C, Kellum, John A, Khan, Feras, Kurz, Michael C, Lotfipour, Shahram, LoVecchio, Frank, Peck-Palmer, Octavia M, Pike, Francis, Prunty, Heather, Sherwin, Robert L, Southerland, Lauren, Terndrup, Thomas, Weissfeld, Lisa A, Yabes, Jonathan, Angus, Derek C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anti-Bacterial Agents - therapeutic use Antibiotics Bacterial Infections - blood Bacterial Infections - diagnosis Bacterial Infections - drug therapy Biomarkers - blood Calcitonin - blood Chronic obstructive pulmonary disease Emergency medical care Emergency Service, Hospital Emergency services FDA approval Female Guideline Adherence Hospitalists Hospitals Humans Illnesses Inappropriate Prescribing - prevention & control Inappropriate Prescribing - statistics & numerical data Infections Male Medicine Middle Aged Patients Pneumonia Pneumonia - drug therapy Practice Guidelines as Topic Practice Patterns, Physicians' - statistics & numerical data Procalcitonin Respiratory tract diseases Respiratory tract infection Respiratory Tract Infections - blood Respiratory Tract Infections - drug therapy Viral infections
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Beschreibung
Zusammenfassung:	Differentiating acute bacterial infection from other causes of lower respiratory tract illness is challenging. In this trial, procalcitonin was investigated as a point-of-care test to aid in determining whether antibiotics were needed in the treatment of these illnesses.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMoa1802670