Representation of Minorities and Elderly Patients in Multiple Myeloma Clinical Trials

Representation of Minorities and Elderly Patients in Multiple Myeloma Clinical Trials

Multiple myeloma (MM) occurs in all races, but the incidence in non‐Hispanic black patients (NHBs) is two to three times higher than in non‐Hispanic white patients (NHWs). We determined the representation of minorities and elderly patients in MM clinical trials. Enrollment data from all therapeutic...

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Veröffentlicht in:The oncologist (Dayton, Ohio) Ohio), 2018-09, Vol.23 (9), p.1076-1078
Hauptverfasser: Duma, Narjust, Azam, Tariq, Riaz, Irbaz Bin, Gonzalez‐Velez, Miguel, Ailawadhi, Sikander, Go, Ronald
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Brief Communications
Clinical trials
Elderly
Female
Hematologic malignancies
Humans
Male
Minorities
Minority Groups
Multiple myeloma
Multiple Myeloma - epidemiology
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Zusammenfassung:Multiple myeloma (MM) occurs in all races, but the incidence in non‐Hispanic black patients (NHBs) is two to three times higher than in non‐Hispanic white patients (NHWs). We determined the representation of minorities and elderly patients in MM clinical trials. Enrollment data from all therapeutic trials reported in ClinicalTrials.gov from 2000 to 2016 were analyzed. Enrollment fraction (EF) was defined as the number of trial enrollees divided by the 2014 MM prevalence. Participation in MM clinical trials varied significantly across racial and ethnic groups; NHWs were more likely to be enrolled in clinical trials (EF 0.18%) than NHBs (EF 0.06%, p 
ISSN:1083-7159
1549-490X
DOI:10.1634/theoncologist.2017-0592