Lansoprazole-Induced Subacute Cutaneous Lupus Erythematosus

Drug induced subacute cutaneous lupus erythematosus (DI-SCLE) mostly affects adults and often occurs on sun-exposed areas.1 DI-SCLE has been shown to be associated with a large number of drugs including calcium channel blockers, statins, and proton pump inhibitors.2 Although the patients with autoimmune diseases have been shown to be more prone to DI-SCLE, the exact pathogenesis of DI-SCLE remains unknown. In patients with DI-SCLE, the histological examination of a skin biopsy often indicates vacuolar degeneration...