Corn Oil Lowers Plasma Cholesterol Compared with Coconut Oil in Adults with Above-Desirable Levels of Cholesterol in a Randomized Crossover Trial

Few trials have examined the effects of coconut oil consumption in comparison with polyunsaturated fatty acid–rich oils such as corn oil. This trial assessed the effects of consuming foods made with corn oil compared with coconut oil on lipids, glucose homeostasis, and inflammation. This was a preli...

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Veröffentlicht in:	The Journal of nutrition 2018-10, Vol.148 (10), p.1556-1563
Hauptverfasser:	Maki, Kevin C, Hasse, Wendy, Dicklin, Mary R, Bell, Marjorie, Buggia, Mary A, Cassens, Martha E, Eren, Fulya
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Adults Aged Analysis of Variance Body mass index Body size Bread - analysis C-reactive protein C-Reactive Protein - metabolism Carbohydrates Cholesterol Cholesterol - blood Cholesterol, HDL - blood Cholesterol, LDL - blood Clinical trials Coconut oil Coconut Oil - pharmacology Coconut Oil - therapeutic use Cocos - chemistry Corn Corn oil Corn Oil - pharmacology Corn Oil - therapeutic use Cross-Over Studies Diet Dietary Fats - pharmacology Dietary Fats - therapeutic use Edible oils Evidence-based medicine Fasting Fatty acids Feeding Behavior Female Food Food consumption Glucose Glucose metabolism Glucose tolerance High density lipoprotein Homeostasis Humans Hypercholesterolemia - blood Hypercholesterolemia - diet therapy inflammation insulin sensitivity Intravenous administration Laboratory testing Lipid metabolism Lipids lipoprotein lipids Low density lipoprotein Male Metabolism Middle Aged Nutrition and Disease Oils & fats Plasma Polyunsaturated fatty acids Protein turnover Proteins Randomization Sensitivity analysis Triglycerides Triglycerides - blood Vegetables Young Adult Zea mays - chemistry
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Zusammenfassung:	Few trials have examined the effects of coconut oil consumption in comparison with polyunsaturated fatty acid–rich oils such as corn oil. This trial assessed the effects of consuming foods made with corn oil compared with coconut oil on lipids, glucose homeostasis, and inflammation. This was a preliminary randomized crossover study of men (n= 12) and women (n= 13) with a mean age of 45.2 y, mean body mass index (in kg/m2) of 27.7, fasting LDL cholesterol ≥115 mg/dL and
ISSN:	0022-3166 1541-6100
DOI:	10.1093/jn/nxy156