A MALDI-TOF MS Approach for Mammalian, Human, and Formula Milks' Profiling

Human milk composition is dynamic, and substitute formulae are intended to mimic its protein content. The purpose of this study was to investigate the potentiality of matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry (MALDI-TOF MS), followed by multivariate data analyses a...

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Veröffentlicht in:Nutrients 2018-09, Vol.10 (9), p.1238
Hauptverfasser: Di Francesco, Laura, Di Girolamo, Francesco, Mennini, Maurizio, Masotti, Andrea, Salvatori, Guglielmo, Rigon, Giuliano, Signore, Fabrizio, Pietrantoni, Emanuela, Scapaticci, Margherita, Lante, Isabella, Goffredo, Bianca Maria, Mazzina, Oscar, Elbousify, Ahmed Ibrahim, Roncada, Paola, Dotta, Andrea, Fiocchi, Alessandro, Putignani, Lorenza
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Sprache:eng
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Zusammenfassung:Human milk composition is dynamic, and substitute formulae are intended to mimic its protein content. The purpose of this study was to investigate the potentiality of matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry (MALDI-TOF MS), followed by multivariate data analyses as a tool to analyze the peptide profiles of mammalian, human, and formula milks. Breast milk samples from women at different lactation stages (2 ( = 5), 30 ( = 6), 60 ( = 5), and 90 ( = 4) days postpartum), and milk from donkeys ( = 4), cows ( = 4), buffaloes ( = 7), goats ( = 4), ewes ( = 5), and camels ( = 2) were collected. Different brands ( = 4) of infant formulae were also analyzed. Protein content (
ISSN:2072-6643
2072-6643
DOI:10.3390/nu10091238