Preterm Neuroimaging and School-Age Cognitive Outcomes

Children born extremely preterm are at risk for cognitive difficulties and disability. The relative prognostic value of neonatal brain MRI and cranial ultrasound (CUS) for school-age outcomes remains unclear. Our objectives were to relate near-term conventional brain MRI and early and late CUS to co...

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Veröffentlicht in:	Pediatrics (Evanston) 2018-07, Vol.142 (1), p.1
Hauptverfasser:	Hintz, Susan R, Vohr, Betty R, Bann, Carla M, Taylor, H Gerry, Das, Abhik, Gustafson, Kathryn E, Yolton, Kimberly, Watson, Victoria E, Lowe, Jean, DeAnda, Maria Elena, Ball, M Bethany, Finer, Neil N, Van Meurs, Krisa P, Shankaran, Seetha, Pappas, Athina, Barnes, Patrick D, Bulas, Dorothy, Newman, Jamie E, Wilson-Costello, Deanne E, Heyne, Roy J, Harmon, Heidi M, Peralta-Carcelen, Myriam, Adams-Chapman, Ira, Duncan, Andrea Freeman, Fuller, Janell, Vaucher, Yvonne E, Colaizy, Tarah T, Winter, Sarah, McGowan, Elisabeth C, Goldstein, Ricki F, Higgins, Rosemary D
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Brain Brain - diagnostic imaging Cerebellum Child Child, Preschool Children Clinical outcomes Cognition Cognition disorders Cognitive ability Cognitive development Cognitive disorders Developmental Disabilities - diagnostic imaging Developmental Disabilities - epidemiology Diagnosis Disabilities Disability Disability Evaluation Echoencephalography - methods Follow-Up Studies Health aspects Hearing loss Humans Impairment Infant Infant, Newborn Infant, Premature Lesions Magnetic resonance imaging Magnetic Resonance Imaging - methods Medical imaging Medical prognosis Model accuracy Neonates Neuroimaging Neuroimaging - methods Neurology Oximetry Paralysis Pediatrics Prognosis Prospective Studies Regression analysis Respiratory tract Substantia alba Ultrasonic imaging Ultrasound
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Beschreibung
Zusammenfassung:	Children born extremely preterm are at risk for cognitive difficulties and disability. The relative prognostic value of neonatal brain MRI and cranial ultrasound (CUS) for school-age outcomes remains unclear. Our objectives were to relate near-term conventional brain MRI and early and late CUS to cognitive impairment and disability at 6 to 7 years among children born extremely preterm and assess prognostic value. A prospective study of adverse early and late CUS and near-term conventional MRI findings to predict outcomes at 6 to 7 years including a full-scale IQ (FSIQ)
ISSN:	0031-4005 1098-4275
DOI:	10.1542/peds.2017-4058