Body mass index modulates the association between CDKAL1 rs10946398 variant and type 2 diabetes among Taiwanese women

Body mass index modulates the association between CDKAL1 rs10946398 variant and type 2 diabetes among Taiwanese women

CDKAL1 rs10946398 is a type 2 diabetes (T2D)-associated variant. It is a new body mass index (BMI)-associated variant in Asian populations. We investigated the association between rs10946398 and T2D among 9908 participants aged 30–70 years based on BMI: normal weight; 18.5 ≤ BMI 

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Veröffentlicht in:Scientific reports 2018-09, Vol.8 (1), p.13235-7, Article 13235
Hauptverfasser: Nfor, Oswald Ndi, Wu, Ming-Fang, Lee, Chun-Te, Wang, Lee, Liu, Wen-Hsiu, Tantoh, Disline Manli, Hsu, Shu-Yi, Lee, Kuan-Jung, Ho, Chien-Chang, Debnath, Tonmoy, Lung, Chia-Chi, Liaw, Yung-Po
Format: Artikel
Sprache:eng
Schlagworte:
692/163/2743/137/773
692/499
Alleles
Body mass index
Body weight
Diabetes
Diabetes mellitus
Diabetes mellitus (non-insulin dependent)
Genotypes
Humanities and Social Sciences
multidisciplinary
Obesity
Overweight
Science
Science (multidisciplinary)
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Zusammenfassung:CDKAL1 rs10946398 is a type 2 diabetes (T2D)-associated variant. It is a new body mass index (BMI)-associated variant in Asian populations. We investigated the association between rs10946398 and T2D among 9908 participants aged 30–70 years based on BMI: normal weight; 18.5 ≤ BMI 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-018-31415-4