In Vitro and In Vivo Activities of Contezolid (MRX-I) against Mycobacterium tuberculosis

The activity of contezolid (MRX-I) against clinical isolates of was evaluated using a microtiter broth dilution assay. MRX-I was as effective as linezolid (LZD) MRX-I and LZD were subsequently studied in BALB/c mice infected intranasally with Erdman. MRX-I and LZD at 100 mg/kg significantly reduced...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Antimicrobial agents and chemotherapy 2018-08, Vol.62 (8)
Hauptverfasser:	Shoen, Carolyn, DeStefano, Michelle, Hafkin, Barry, Cynamon, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Antitubercular Agents Experimental Therapeutics Mycobacterium tuberculosis Oxazolidinones Pyridones Tuberculosis, Multidrug-Resistant
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!