EADSG Guidelines: Insulin Therapy in Diabetes

Executive Summary and Recommendations A diagnosis of diabetes or hyperglycemia should be confirmed prior to ordering, dispensing, or administering insulin (A) . Insulin is the primary treatment in all patients with type 1 diabetes mellitus (T1DM) (A) . Typically, patients with T1DM will require initiation with multiple daily injections at the time of diagnosis. This is usually short-acting insulin or rapid-acting insulin analogue given 0 to 15 min before meals together with one or more daily separate injections of intermediate or long-acting insulin. Two or three premixed insulin injections per day may be used (A) . The target glycated hemoglobin A1c (HbA1c) for all children with T1DM, including preschool children, is recommended to be