Serotonin induces parathyroid hormone-related protein in goat mammary gland

Abstract During lactation, large amounts of calcium are exported from the mammary gland into milk to ensure skeletal growth of the offspring. Recent studies revealed that serotonin (5-HT) is essential to stimulate skeletal calcium resorption for milk synthesis. Our objective was to explore the corre...

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Veröffentlicht in:	Journal of animal science 2018-04, Vol.96 (3), p.1010-1016
Hauptverfasser:	Zang, W J, Li, H, Zhang, Z F, QuZhen, R, CuoMu, Y Z, Zhang, D K, Luo, J, Loor, J J, Zheng, H L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphatase Animals Biosynthesis Bone resorption Ca2+-transporting ATPase Calcium Calcium - blood Calcium - metabolism Calcium ions Calcium-sensing receptors Correlation analysis Epithelial cells Female Gene expression Goats Goats - genetics Goats - physiology Lactation Lactation and Mammary Gland Biology Mammary gland Mammary Glands, Animal - metabolism Milk - chemistry mRNA Offspring Parathyroid Parathyroid hormone Parathyroid hormone-related protein Parathyroid Hormone-Related Protein - blood Parathyroid Hormone-Related Protein - metabolism Parturition Postpartum Postpartum Period Pregnancy Proteins RNA, Messenger - genetics Serotonin Serotonin - metabolism Therapeutic applications Tryptophan Tryptophan hydroxylase
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