Genetic Vulnerability of GPCRs: A Call to Action

G-protein-coupled receptors (GPCRs) are the targets for many drugs, but the response shows interindividual variability. The ‘one-drug-fits-all’ approach has been challenged by evidence showing multiple human genetic variants of GPCRs. Identification and characterization of GPCR variants must be unde...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Trends in biochemical sciences (Amsterdam. Regular ed.) 2018-04, Vol.43 (4), p.227-229
1. Verfasser:	Liggett, Stephen B.
Format:	Artikel
Sprache:	eng
Schlagworte:	asthma coupling G protein Genetic Variation heart failure Humans Mutation polymorphism Receptors, G-Protein-Coupled - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!