Hormetic dose response to L-ascorbic acid as an anti-cancer drug in colorectal cancer cell lines according to SVCT-2 expression

L -Ascorbic acid (vitamin C, AA) exhibits anti-cancer effects with high-dose treatment through the generation of reactive oxygen species (ROS) and selective damage to cancer cells. The anti-cancer effects of L -ascorbic acid are determined by sodium-dependent vitamin C transporter 2 (SVCT-2), a tran...

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Veröffentlicht in:Scientific reports 2018-07, Vol.8 (1), p.11372-9, Article 11372
Hauptverfasser: Cho, Sungrae, Chae, Jin Sung, Shin, Hocheol, Shin, Yujeong, Song, Haeun, Kim, Youngwook, Yoo, Byong Chul, Roh, Kangsan, Cho, Seungchan, Kil, Eui-joon, Byun, Hee-seong, Cho, Sang-ho, Park, Seyeon, Lee, Sukchan, Yeom, Chang-Hwan
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Sprache:eng
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