Widefield compressive multiphoton microscopy

Widefield compressive multiphoton microscopy

A single-pixel compressively sensed architecture is exploited to simultaneously achieve a 10× reduction in acquired data compared with the Nyquist rate, while alleviating limitations faced by conventional widefield temporal focusing microscopes due to scattering of the fluorescence signal. Additiona...

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Veröffentlicht in:Optics letters 2018-06, Vol.43 (12), p.2989-2992
Hauptverfasser: Alemohammad, Milad, Shin, Jaewook, Tran, Dung N, Stroud, Jasper R, Chin, Sang Peter, Tran, Trac D, Foster, Mark A
Format: Artikel
Sprache:eng
Schlagworte:
Adaptive sampling
Data acquisition
Fluorescence
Microscopes
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Beschreibung
Zusammenfassung:A single-pixel compressively sensed architecture is exploited to simultaneously achieve a 10× reduction in acquired data compared with the Nyquist rate, while alleviating limitations faced by conventional widefield temporal focusing microscopes due to scattering of the fluorescence signal. Additionally, we demonstrate an adaptive sampling scheme that further improves the compression and speed of our approach.
ISSN:0146-9592
1539-4794
DOI:10.1364/OL.43.002989