Impact of viral upper respiratory tract infection on the concentration of nasopharyngeal pneumococcal carriage among Kenyan children

Viral upper respiratory tract infection (URTI) predisposes to bacterial pneumonia possibly by facilitating growth of bacteria such as Streptococcus pneumoniae colonising the nasopharynx. We investigated whether viral URTI is temporally associated with an increase in nasopharyngeal pneumococcal conce...

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Veröffentlicht in:	Scientific reports 2018-07, Vol.8 (1), p.11030-8, Article 11030
Hauptverfasser:	Morpeth, Susan C., Munywoki, Patrick, Hammitt, Laura L., Bett, Anne, Bottomley, Christian, Onyango, Clayton O., Murdoch, David R., Nokes, D. James, Scott, J. Anthony G.
Format:	Artikel
Sprache:	eng
Schlagworte:	38/77 631/326/1320 631/326/421 692/420/254 692/699/255/1318 692/700/1720/3187 Child, Preschool Children Female Humanities and Social Sciences Humans Infant Kenya Longitudinal Studies Male multidisciplinary Nasopharynx Polymerase Chain Reaction Respiratory tract Respiratory tract diseases Respiratory tract infection Respiratory Tract Infections - microbiology Respiratory Tract Infections - virology Rhinovirus Rhinovirus - pathogenicity Science Science (multidisciplinary) Streptococcus infections Streptococcus pneumoniae - pathogenicity Vaccines Viral infections
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Zusammenfassung:	Viral upper respiratory tract infection (URTI) predisposes to bacterial pneumonia possibly by facilitating growth of bacteria such as Streptococcus pneumoniae colonising the nasopharynx. We investigated whether viral URTI is temporally associated with an increase in nasopharyngeal pneumococcal concentration. Episodes of symptomatic RSV or rhinovirus URTI among children
ISSN:	2045-2322 2045-2322
DOI:	10.1038/s41598-018-29119-w