MOG-IgG-associated disease has a stereotypical clinical course, asymptomatic visual impairment and good treatment response

MOG-IgG-associated disease has a stereotypical clinical course, asymptomatic visual impairment and good treatment response

Objectives We investigated the clinical characteristics and treatment response in myelin oligodendrocyte glycoprotein antibody (MOG-IgG)-associated disease and looked for evidence of subclinical disease. Methods We prospectively evaluated the frequency and pattern of relapse, tested afferent visual...

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Veröffentlicht in:Multiple sclerosis journal - experimental, translational and clinical translational and clinical, 2018-07, Vol.4 (3), p.2055217318787829-2055217318787829
Hauptverfasser: Pandit, Lekha, Mustafa, Sharik, Nakashima, Ichiro, Takahashi, Toshyuki, Kaneko, Kimhiko
Format: Artikel
Sprache:eng
Schlagworte:
Inflammatory diseases
Original Research Paper
Visual impairment
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Zusammenfassung:Objectives We investigated the clinical characteristics and treatment response in myelin oligodendrocyte glycoprotein antibody (MOG-IgG)-associated disease and looked for evidence of subclinical disease. Methods We prospectively evaluated the frequency and pattern of relapse, tested afferent visual function and monitored treatment response in 42 south Asian patients from a single centre. Results Eighteen patients (42.9%) had monophasic and 24 (57.1%) a relapsing course. Disease duration was longer (P
ISSN:2055-2173
2055-2173
DOI:10.1177/2055217318787829