Oncogenic miR-425-5p is associated with cellular migration, proliferation and apoptosis in renal cell carcinoma

Oncogenic miR-425-5p is associated with cellular migration, proliferation and apoptosis in renal cell carcinoma

An increasing number of studies have demonstrated the function of microRNAs (miRNAs) in the initiation and development of various types of cancer. Among them, miR-425-5p is proven to serve an important function in several types of cancer, including gastric, cervical cancer, and hepatocellular carcin...

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Veröffentlicht in:Oncology letters 2018-08, Vol.16 (2), p.2175-2184
Hauptverfasser: Quan, Jing, Li, Yawen, Pan, Xiang, Lai, Yulin, He, Tao, Lin, Canbin, Zhou, Liang, Zhao, Liwen, Sun, Shuolei, Ding, Yu, Tao, Lingzhi, Hu, Yimin, Wu, Xionghui, Chen, Zebo, Zhang, Fangting, Ye, Jing, Ni, Liangchao, Lai, Yongqing
Format: Artikel
Sprache:eng
Schlagworte:
Alzheimer's disease
Apoptosis
Cancer
Care and treatment
Cell cycle
Cell division
Cell growth
Cervical cancer
Development and progression
Gene expression
Genetic aspects
Health aspects
Kidney cancer
Kinases
Laboratories
Liver cancer
MicroRNA
Oncology
Renal cell carcinoma
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Zusammenfassung:An increasing number of studies have demonstrated the function of microRNAs (miRNAs) in the initiation and development of various types of cancer. Among them, miR-425-5p is proven to serve an important function in several types of cancer, including gastric, cervical cancer, and hepatocellular carcinoma. However, the function of miR-425-5p in renal cell carcinoma (RCC) remains unclear. In the present study, it was demonstrated that the expression level of miR-425-5p was upregulated in RCC tissues and cell lines compared with normal tissues and cell lines (P
ISSN:1792-1074
1792-1082
DOI:10.3892/ol.2018.8948