Computational Convolution of SELDI Data for the Diagnosis of Alzheimer's Disease

Alzheimer's disease is rapidly becoming an endemic for people over the age of 65. A vital path towards reversing this ominous trend is the building of reliable diagnostic devices for definite and early diagnoses in lieu of the longitudinal, usually inconclusive and non-generalize-able methods c...

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Veröffentlicht in:Biotech (Basel) 2018-05, Vol.7 (2), p.14
Hauptverfasser: Anyaiwe, Destiny E O, Singh, Gautam B, Wilson, George D, Geddes, Timothy J
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Sprache:eng
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Zusammenfassung:Alzheimer's disease is rapidly becoming an endemic for people over the age of 65. A vital path towards reversing this ominous trend is the building of reliable diagnostic devices for definite and early diagnoses in lieu of the longitudinal, usually inconclusive and non-generalize-able methods currently in use. In this article, we present a survey of methods for mining pools of mass spectrometer saliva data in relation to diagnosing Alzheimer's disease. The computational methods provides new approaches for appropriately gleaning latent information from mass spectra data. They improve traditional machine learning algorithms and are most fit for handling matrix data points including solving problems beyond protein identifications and biomarker discovery.
ISSN:2571-5135
2571-5135
2673-6284
DOI:10.3390/ht7020014