Psychological outcomes and surgical decisions after genetic testing in women newly diagnosed with breast cancer with and without a family history
In patients with early breast cancer, personal and tumour characteristics other than family history are increasingly used to prompt genetic testing to guide women's cancer management (treatment-focused genetic testing, 'TFGT'). Women without a known strong family history of breast and...
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Veröffentlicht in: | European journal of human genetics : EJHG 2018-07, Vol.26 (7), p.972-983 |
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Hauptverfasser: | , , , , , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | In patients with early breast cancer, personal and tumour characteristics other than family history are increasingly used to prompt genetic testing to guide women's cancer management (treatment-focused genetic testing, 'TFGT'). Women without a known strong family history of breast and/or ovarian may be more vulnerable to psychological sequelae arising from TFGT. We compared the impact of TFGT in women with (FH+) and without (FH-) a strong family history on psychological adjustment and surgical decisions. Women aged |
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ISSN: | 1018-4813 1476-5438 |
DOI: | 10.1038/s41431-017-0057-3 |