Primary small cell carcinoma of the larynx. Survival time of 47 months. Case report

Small cell carcinoma (SCC) of the larynx is a rare type of neuroendocrine carcinoma (NEC), few cases of which have been described in the literature. The prognosis for this type of carcinoma is poor, with a survival time typically not exceeding two years. We describe the case of a 54-year-old male patient with a primary tumor in the right ventricular band and a biopsy compatible with SCC. The patient underwent radiotherapy (RT) and concomitant chemotherapy (QT) and, after a relapse at 17 months, underwent total laryngectomy with bilateral neck dissection. The survival time was 47 months. Further studies are required to elucidate the possible causes of the better prognosis in some cases. •The incidence of SCC of the larynx has increased in recent decades, although it still remains rare.•The survival rates are 16% for two years and 5% for five years.•We describe the case of a 54-year-old male who is still alive, a survival time of more than 44 months.