Nanoparticle transport pathways into tumors
Two transport pathways (interendothelial and transendothelial routes) have long been proposed for entry of nanoparticles from the blood circulation into solid tumors. We examine and discuss available evidence supporting interendothelial and transendothelial transport processes and suggest new avenue...
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| Veröffentlicht in: | Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology 2018, Vol.20 (6), p.169-4, Article 169 |
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| container_title | Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology |
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| creator | Moghimi, S. M. Simberg, D. |
| description | Two transport pathways (interendothelial and transendothelial routes) have long been proposed for entry of nanoparticles from the blood circulation into solid tumors. We examine and discuss available evidence supporting interendothelial and transendothelial transport processes and suggest new avenues for re-evaluating these pathways. Understanding of integrative mechanisms controlling nanoparticle extravasation into tumors is important for improving engineering and performance of anti-cancer nanopharmaceuticals. |
| doi_str_mv | 10.1007/s11051-018-4273-8 |
| format | Article |
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| ispartof | Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology, 2018, Vol.20 (6), p.169-4, Article 169 |
| issn | 1388-0764 1572-896X |
| language | eng |
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| source | Springer Online Journals Complete |
| subjects | Blood circulation Cancer Characterization and Evaluation of Materials Chemistry and Materials Science Extravasation Inorganic Chemistry Lasers Materials Science Nanoparticles Nanotechnology Optical Devices Optics Perspectives Photonics Physical Chemistry Solid tumors Transport processes Tumors Unifying Concepts for Nanoscience and Nanosystems: 20th Anniversary Issue |
| title | Nanoparticle transport pathways into tumors |
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