Nanoparticle transport pathways into tumors

Nanoparticle transport pathways into tumors

Two transport pathways (interendothelial and transendothelial routes) have long been proposed for entry of nanoparticles from the blood circulation into solid tumors. We examine and discuss available evidence supporting interendothelial and transendothelial transport processes and suggest new avenue...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology 2018, Vol.20 (6), p.169-4, Article 169
Hauptverfasser: Moghimi, S. M., Simberg, D.
Format: Artikel
Sprache:eng
Schlagworte:
Blood circulation
Cancer
Characterization and Evaluation of Materials
Chemistry and Materials Science
Extravasation
Inorganic Chemistry
Lasers
Materials Science
Nanoparticles
Nanotechnology
Optical Devices
Optics
Perspectives
Photonics
Physical Chemistry
Solid tumors
Transport processes
Tumors
Unifying Concepts for Nanoscience and Nanosystems: 20th Anniversary Issue
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Two transport pathways (interendothelial and transendothelial routes) have long been proposed for entry of nanoparticles from the blood circulation into solid tumors. We examine and discuss available evidence supporting interendothelial and transendothelial transport processes and suggest new avenues for re-evaluating these pathways. Understanding of integrative mechanisms controlling nanoparticle extravasation into tumors is important for improving engineering and performance of anti-cancer nanopharmaceuticals.
ISSN:1388-0764
1572-896X
DOI:10.1007/s11051-018-4273-8