Flecainide toxicity in renal failure

Flecainide toxicity in renal failure

Flecainide, a class Ic antiarrhythmic, is used for the prevention of paroxysmal supraventricular tachycardia, paroxysmal atrial fibrillation/flutter, and sustained ventricular tachycardia. Flecainide is primarily metabolized by the liver and to a lesser extent (30%) is excreted unchanged in the kidn...

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Veröffentlicht in:Proceedings - Baylor University. Medical Center 2018-07, Vol.31 (3), p.328-330
Hauptverfasser: Subedi, Rogin, Dean, Ryan K, Chaudhary, Arbind, Szombathy, Tamas
Format: Artikel
Sprache:eng
Schlagworte:
Cardiac arrhythmia
Case Studies
Drug dosages
Edema
Electrocardiography
Heart
Morphology
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Zusammenfassung:Flecainide, a class Ic antiarrhythmic, is used for the prevention of paroxysmal supraventricular tachycardia, paroxysmal atrial fibrillation/flutter, and sustained ventricular tachycardia. Flecainide is primarily metabolized by the liver and to a lesser extent (30%) is excreted unchanged in the kidney. We present a case of flecainide toxicity in the setting of renal impairment that was successfully treated with intravenous sodium bicarbonate.
ISSN:0899-8280
1525-3252
DOI:10.1080/08998280.2018.1463042